PRODUCT NAME:
Product Name: Interleukin-6 CLIA Kit (Chemiluminescence Immunoassay)
Abbreviation: IL-6
INTENDED USE:
Interleukin-6 CLIA Kit (Chemiluminescence Immunoassay) is an in vitro diagnostic test for the
quantitative detection of IL-6 (Interleukin-6) in human serum and plasma specimen. This product is
intended to be used by laboratory professional workers only. Normal IL-6 results do not preclude
development of a severe inflammatory response and should not be used as the sole basis for patient
management decisions. Results must be combined with clinical observations, patient history, other
laboratory parameters, and epidemiological information.
Interleukin (IL) is a group of cytokines (secreted signaling molecules). It was first discovered in
leukocytes as a means of intercellular signaling. In fact, interleukin can be produced by a variety of
cells. The function of the immune system is largely dependent on interleukins. Some rare interleukin
deficiencies are often associated with autoimmune diseases or immunodeficiencies. IL-6 is a
multifunctional 26 kD protein and consists of 184 amino acids. Originally it was only found that it
was synthesized in leukocytes and was named after that as it played a role among leukocytes. With
the continuous progress of research, it has been gradually found that not only activated lymphocytes
and monocyte-macrophages can synthesize and secrete IL-6, but also bone marrow cells and some
tumor cells can also produce IL-6. As an important mediator produced by the body in the immune
response, it has a variety of biological activities. IL-6 is a pleiotropic cytokine that regulates a
variety of cellular functions, including cell proliferation, cell differentiation, immune defense
mechanisms, and hematopoiesis.