Apolipoprotein E(APOE) Determination Reagent(Immunoturbidimetry) is an in vitro diagnostic quantitative test kit. APOE4 variant, which is associated with increased risk of late-onset (age >60-65) Alzheimer's disease (AD). Testing may be considered for patients with dementia to supplement information from clinical and other evaluations. APOE genotyping supplies supplementary information for the clinical diagnosis of Alzheimer's disease.