Angiotensin Converting Enzyme(ACE) Determination Reagent(FAPGG substrate method) is an in vitro diagnostic test kit. It is useful in assessing the response of sarcoidosis to corticosteroid therapy.

ACE is a dipeptidyl carboxypeptidase. Increases are less frequent when sarcoidosis is inactive.6 Some 80% to 90% of patients with demonstrably active sarcoidosis have elevated serum ACE. It functions to split dipeptides from the free carboxy end of a variety of polypeptides including angiotensin I and bradykinin.