Intended use: Clozapine determination kit is an in vitro diagnostic test for the detection of  clozapine in human blood.

Clozapine is used to treat certain mental/mood disorders (schizophrenia, schizoaffective disorders). Clozapine may also help prevent suicide in people who are likely to try to harm themselves. Clozapine belongs to a class of drugs known as atypical antipsychotics.

Serum concentration of CLZ is associated with clinical response and dose-dependents side effects, where generalized tonic-clonic seizures are most critical. Thus, therapeutic drug monitoring (TDM) of CLZ may guide individual dosing to reach target exposure and prevent dose-dependent side effects.