Alpha-fetoprotein Determination Kit


Alpha-fetoprotein Determination Kit (Fluorescence Immunochromatographic Assay) Abbreviation: AFP 


Alpha-fetoprotein Determination Kit is an in vitro diagnostic test for the quantitative detection of alpha-fetoprotein in human serum, plasma and whole blood (venous and fingerstick) specimens. Alpha-fetoprotein (AFP) is a plasma protein produced by the embryonic yolk sac and fetal liver, with a molecular weight of 70,000 Daltons. AFP levels in serum, amniotic fluid, and urine can be used as screening tests for congenital disabilities, chromosomal abnormalities, and other tumors and pathologies in adults. This tumor marker is a glycoprotein encoded by the AFP gene on chromosome 4q25. Prenatal levels of developing human embryos rise from the first trimester of gestation and begin to decline after 32 weeks of gestation. Studies have shown that AFP levels are significantly elevated in the serum of patients with primary liver cancer and nonseminoma testicular cancer. Combined detection of AFP and human chorionic gonadotropin (HCG) can improve the diagnosis of testicular seminoma, and elevated serum AFP levels in patients with pure seminoma indicate the presence of nonseminoma components or liver metastases. Clinically, it is mainly used for the auxiliary diagnosis of primary hepatocellular carcinoma and the evaluation of treatment effect and dynamic in patients with liver cancer. It can also be used to monitor pregnancy-related abnormalities and should not be used as the basis for early diagnosis or confirmation of malignant tumors.