PRODUCT NAME:

Product Name: Interleukin-1β CLIA Kit (Chemiluminescence Immunoassay) Abbreviation: IL-1β 

INTENDED USE:

Interleukin-1β CLIA Kit (Chemiluminescence Immunoassay) is an in vitro diagnostic test for the quantitative detection of interleukin-1β (IL-1β) in human serum and plasma specimen. This product is intended to be used by laboratory professional workers only. This kit is used for auxiliary diagnosis. Results must be combined with clinical observations, patient history, other laboratory parameters, and epidemiological information for comprehensive analysis. Interleukin (IL) is a group of cytokines (secreted signaling molecules). It was first discovered to be expressed in leukocytes as a means of intercellular signal transmission. In fact, interleukins can be produced by a variety of cells. The function of the immune system is largely dependent on interleukins. Some rare interleukin deficiencies are often accompanied by autoimmune diseases or immunodeficiency. IL-1β plays a central role in immune regulation and inflammatory response processes. Conditions such as rheumatoid and colitis are also associated with excessive production of IL-1β. IL-1β precursor is synthesized in cells and has no biological activity. It is cleaved into a mature form by IL-1β-converting enzyme (ICE) and then excreted out of the cell. The precursor of human IL-1β has 269 amino acids, and after being cleaved by ICE, an active protein of 153 amino acids is formed. Detecting the content of IL-1β can assist in monitoring the immune status and inflammatory response of the body