Homocysteine Determination Reagent(Cydle Enzyme Method) is an in vitro diagnostic quantitative test kit. The test is used for screening patients who may be at risk for heart disease and stroke. Homocysteine can be considered to be an independent risk factor for the development of cardiovascular disease.1-3 Patients with cardiovascular disease, including heart disease, stroke, peripheral vascular disease, and thromboembolic disease generally have higher homocysteine levels than matched controls.