PRODUCT NAME:

Free Prostate Specific Antigen Determination Kit (Fluorescence Immunochromatographic Assay） Abbreviation: fPSA

INTENDED USE:

Free Prostate Specific Antigen Determination Kit is an in vitro diagnostic test for the quantitative detection of fPSA in human serum, plasma and whole blood specimens. It is usually used in combination with a total PSA determination kit to calculate the percentage of free PSA. For men ≥50 years of age, with total PSA between 4- 10ng/ml and normal digital rectal examination results, the percentage of free PSA is helpful for the differential diagnosis of prostate cancer and other benign prostate diseases. 

Prostate specific antigen (PSA) is secreted by prostate epithelial cells. It is a protein of the kininase family and exists in prostate tissue and semen. The PSA content in normal human serum is minimal. PSA mainly exists in three forms in serum: free prostate specific antigen (fPSA), which accounts for 10%-30% of the total prostate specific antigen (tPSA); complex formed by the combination of prostate specific antigen and α1-antichymotrypsin (PSA-ACT); the complex formed by the combination of prostate specific antigen and α2-macroglobulin (PSA-α2M). The latter two forms are collectively referred to as binding prostate specific antigen. The main physiological function of PSA is to prevent semen from coagulating. It has extremely high tissue and organ specificity and is currently the preferred marker for the diagnosis of prostate cancer